Graduate Courses of Instruction in Chemistry
CHEM 110b Instrumental Analytical Chemistry
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Prerequisite: Satisfactory grade(s) in CHEM 41a and b, CHEM 59a and b, or equivalent. Laboratory fee: $45.
Techniques of instrumental chemical analysis. Application of instrumental methods to the separation and analysis of complex mixtures. Students rotate through ongoing research laboratories. Data treatment includes computers in the analytical chemistry laboratory. Two afternoons per week; approximately two hours of laboratory lecture and six hours of laboratory per week. Offered on request.
Staff
CHEM 121a Inorganic Chemistry I, Lectures
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Prerequisite: A satisfactory grade in CHEM 25a and b.
Simple bonding theory. Symmetry, structure, and bonding in inorganic compounds. Solid-state chemistry; ionic and electronic conductors. Applications of group theory and bonding theory to main group compounds and transition metal complexes. Coordination chemistry: isomerism, structure, and reactions. Usually offered every year.
Mr. Foxman
CHEM 122b Inorganic Chemistry II, Lectures
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Prerequisite: A satisfactory grade in CHEM 25a and b.
Molecular orbital theory in organometallic chemistry. Acid-base concepts. Introduction to the synthesis, structure, and applications of organotransition metal compounds. Usually offered every year.
Mr. Ozerov
CHEM 123b Bioinorganic Chemistry
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Prerequisite: A satisfactory grade in CHEM 25a and b.
Bioinorganic chemistry involves the study of metal species in biological systems. Nearly one-third of proteins contain a metal cofactor. These cofactors catalyze an enormous breadth of chemical reactions, including many not yet accessible through conventional syntheses. Usually offered every second year.
Mr. Agar
CHEM 129b Special Topics in Inorganic Chemistry: Introduction to X-Ray Structure Determination
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Topics include basic diffraction and space group theory, practical manipulations of crystals and X-ray diffraction equipment, solving crystal structures, and interpretation of structural chemistry. Course features self-paced exercises on PCs. Usually offered every second year.
Mr. Foxman
CHEM 130a Advanced Organic Chemistry: Structure
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Prerequisite: A satisfactory grade in CHEM 25a and b, or the equivalent.
Chemical bonding and structure, stereochemical principles and conformational analysis, organic reaction mechanisms, structures and activities of reactive intermediates, and pericyclic reactions. Usually offered every year.
Mr. Yu
CHEM 131a Advanced Organic Chemistry: Topics in Structure and Reactivity
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Prerequisite: A satisfactory grade in CHEM 25a and b, or the equivalent.
Broad coverage of a variety of transformations involving additions, eliminations, substitutions, oxidations, reductions, and rearrangements. Usually offered every year.
Staff
CHEM 132b Advanced Organic Chemistry: Spectroscopy
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Prerequisite: A satisfactory grade in CHEM 25a and b, or the equivalent.
Application of spectroscopy to the elucidation of structure and stereochemistry of organic compounds, with emphasis on modern NMR and MS methods. Usually offered every year.
Mr. Snider
CHEM 134b Advanced Organic Chemistry: Synthesis
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Prerequisite: A satisfactory grade in CHEM 25a and b, or the equivalent.
Modern synthetic methods are covered, with an emphasis on mechanism and stereochemical control. Formation of carbon-carbon single and double bonds and carbocycles and procedures for oxidation, reduction, and functional group interchange are discussed. Selected total syntheses are examined. Usually offered every year.
Mr. Deng
CHEM 135a Advanced Organic Chemistry: Synthesis II
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Prerequisite: CHEM 25b or permission of the instructor.
The application of asymmetric and catalytic methods in organic synthesis is illustrated, with an emphasis on metal catalysts and stereoselectivity. Examples of trial-and-error discoveries and rational design of superior catalysts in a wide range of important reactions including hydrogenation, epoxidation, dihydroxylation, C-H activation, and C-C bond forming reactions are covered. Usually offered every second year.
Mr. Yu
CHEM 137b The Chemistry of Organic Natural Products
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Prerequisite: A satisfactory grade in CHEM 25a and b, or the equivalent.
Natural products chemistry is surveyed within a biosynthetic framework. Occurrence, isolation, structure elucidation, biosynthesis, and biomimetic synthesis are covered with an emphasis on modern methods of establishing biosynthesis and biomimetic syntheses. Usually offered every second year.
Mr. Snider
CHEM 141a Physical Chemistry: Thermodynamics and Statistical Thermodynamics
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Prerequisite: Satisfactory grade in CHEM 11a/15a and CHEM 11b/15b or equivalent. MATH 10a,b or equivalent. PHYS 11a,b or 15a,b or equivalent. Organic chemistry is also recommended.
Classical and statistical thermodynamics; principles, tools, and applications in chemistry and biology. Usually offered every year.
Staff
CHEM 142a Physical Chemistry: Quantum Mechanics and Spectroscopy
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Prerequisite: A satisfactory grade in CHEM 11a/15a and CHEM 11b/15b or equivalent; Math 10a,b or equivalent, Phys 11a,b or 15a,b or equivalent. Organic chemistry is also recommended.
Solutions to the Schrodinger equation of relevance to spectroscopic methods such as UV/visible spectroscopy, nuclear magnetic resonance and infrared spectroscopy; introduction to quantum mechanical calculations and computational methods, density matrix and operator formalisms. Usually offered every year.
Staff
CHEM 143b Physical Chemistry: Kinetics, Dynamics, and Transport
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Prerequisite: A satisfactory grade in CHEM 11a/15a and CHEM 11b/15b or equivalent; Math 10a,b or equivalent, Phys 11a,b or 15a,b or equivalent. Organic chemistry is also recommended.
Macroscopic kinetics: elementary reactions and rate laws. Kinetic study of reaction mechanisms: techniques for kinetic measurements, fast reactions, treatment of kinetic data. Microscopic kinetics: molecular dynamics, transition state theory, reactions in the gas phase and in solution. Catalytic and chain reactions, enzyme kinetics. Nonlinear dynamics: chemical oscillations and waves. Usually offered every other year.
Staff
CHEM 144a Physical Chemistry: Computational Chemistry
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Prerequisite: A satisfactory grade in CHEM 11a/15a and CHEM 11b/15b or equivalent; Math 10a,b or equivalent, Phys 11a,b or 15a,b or equivalent. Organic chemistry is also recommended.
Topics in computational chemistry: applications of quantum mechanics to structural and spectroscopic analysis of small molecules; molecular dynamics and Monte Carlo simulations of biomacromolecules. Standard computational programs are used by students to perform homework exercises. Usually offered every other year.
Mr. Jordan
CHEM 146a Single Molecular Spectroscopy
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Prerequisite: A satisfactory grade in CHEM 11a/15a and CHEM 11b/15b or equivalent; MATH 10a,b or equivalent, PHYS 11a,b or PHYS 15 a,b, or equivalent.
Studies single molecule spectroscopy techniques including fluorescence microscopy experiments, laser tweezers, magnetic tweezers, and atomic force microscopy, along with their applications to chemical and biological systems. Usually offered every second year.
Ms. Gershenson
CHEM 147b Physical Chemistry - Mass Spectrometry
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Prerequisite: A satisfactory grade in CHEM 11b/15b or equivalent or permission of the instructor. Organic chemistry is also recommended.
The process of ionization, ion separation, and ion detection is taught at the theoretical level, and applied to the understanding of modern mass spectrometry. Usually offered every second year.
Mr. Agar
CHEM 150b Special Topics in Chemistry
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Topics vary from year to year. Usually offered every third year.
Staff
(200 and above) Primarily for Graduate Students
CHEM 200a Advanced Chemistry Laboratory I
Usually offered every year.
Staff
CHEM 200b Advanced Chemistry Laboratory II
Usually offered every year.
Staff
CHEM 200e Advanced Chemistry Laboratory I
Usually offered every year.
Staff
CHEM 220c Inorganic Chemistry Seminar
Required of graduate students in inorganic chemistry every semester.
Staff
CHEM 224b Chemistry of Organometallic Compounds
The chemistry of organo-transition metal complexes, including their structures, bonding, reactivity, and use in industrial processes and organic synthesis. Usually offered every second year.
Mr. Ozerov
CHEM 230c Organic Chemistry Seminar
Required of graduate students in organic chemistry every semester.
Staff
CHEM 240c Physical Chemistry Seminar
Required of graduate students in physical chemistry every semester.
Staff
CHEM 243b Statistical Thermodynamics
Elementary statistical mechanics of ensembles of molecules and applications to thermodynamic systems. Usually offered every third year.
Mr. Jordan
CHEM 245a Ultrafast Spectroscopy
Ultrafast laser-based spectroscopy techniques and their applications to chemical and biological systems are presented. Topics include the generation of femtosecond laser pulses, pump-probe spectroscopy, time and frequency domain spectroscopy, and ultrafast dynamics of chemical reactions and biomolecular motions. Usually offered every third year.
Ms. Gershenson
CHEM 246b Advanced NMR Spectroscopy
A detailed discussion of modern NMR methods will be presented. The course is designed so as to be accessible to nonspecialists, but still provide a strong background in the theory and practice of modern NMR techniques. Topics include the theory of pulse and multidimensional NMR experiments, chemical shift, scalar and dipolar coupling, NOE, spin-operator formalism, heteronuclear and inverse-detection methods, Hartmann-Hahn and spin-locking experiments. Experimental considerations such as pulse sequence design, phase cycling, and gradient methods will be discussed. Guest lecturers will provide insight into particular topics such as solid-state NMR and NMR instrumental design. Usually offered every third year.
Mr. Pochapsky
CHEM 298a Independent Study
Usually offered every year.
Staff
CHEM 401d Dissertation Research
Independent research for the Ph.D degree. Specific sections for individual faculty members as requested.
Staff
Chemistry Colloquium
Lectures by faculty and invited speakers. Required of all graduate students.
Noncredit.
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